Managing Disease and Staying Healthy.

Leaky Gut

Leaky gut is a name used to describe intestinal or bowel hyper permeability. Tight junctions (TJ's) represent the major barrier within the pathway between intestinal epithelial cells, that line the digestion tract.

Disruption of TJ's leads to intestinal hyper permeability (the so-called "leaky gut") which has been proposed by some researchers to involve a relationship with acute and chronic diseases such as systemic inflammatory response syndrome (SIRS), inflammatory bowel disease, type-1 diabetes, allergies, asthma, and autism.